How polar compounds
like NaCl solubilise in water?
Water basically
dissolves polar solutes by hydrating and stabilizing their ions, weakening the electrostatic interaction between them
and thus counteracting their tendency to associate in a crystalline lattice.
Water is effective
in screening the electrostatic interactions between dissolved ions because it
has high dielectric constant (a physical property that reflects the number of
dipoles in a solvent).
Entropy increases as
crystalline substances dissolve
Do you know the reason why CO2
and O2 requires RBC to transport them to different organs and cells in the
body?
May be because they
are non polar gases which can not dissolve in water and therefore needs a
carrier to transport them to the different organs or cells.
Nonpolarity and
decreased entropy property of the gas will makes them very poorly soluble in
water.
How weak
interactions like vanderwaal's weak interaction will be crucial for
macromolecules structure and function?
The formation of
each of the weak interactions contribute to net decrease in the free energy of
the system. Stability as measured by the equilibrium constant of the binding
reaction varies exponentially with the binding energy. Most stable
macromolecules is usually that in which weak interactions are maximized.
Tightly bound water
molecules are very important for many proteins Inorder to perform their
functions.
Which RNA polymerase does α-amanitin inhibits and how?
RNA
polymerase II. α-amanitin actually is used to determine the type of RNA polymerase
present. It interacts with the bridge helix in the RNA pol II which interferes
the translocation of RNA and DNA needed to empty the site for next round of RNA
synthesis.
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